The Correlation of Routine Tear Function Tests and Conjunctival Impression Cytology in Dry Eye Syndrome
Korean Journal of Ophthalmology
;
: 122-129, 2014.
Article
in English
| WPRIM
| ID: wpr-147480
ABSTRACT
PURPOSE:
To establish the strength of the association between routine tear function tests and conjunctival impression cytology (CIC) and to determine whether they simulate the morphological and cytological changes that occur on the ocular surface in dry eye. What are the sensitivity, specificity and positive predictive values of these tests when CIC is considered the gold standard?METHODS:
The tear film profile included tear film break up time (TBUT), Schirmer's-1, Rose Bengal scores (RBS), and impression cytology. CIC samples were obtained from the inferior bulbar conjunctiva and stained with periodic acid-Schiff and counter stained with hematoxylin and eosin.RESULTS:
The mean Schirmer's value was 11.66 +/- 5.90 in patients and 17.17 +/- 2.97 in controls (p Schirmer's > RBS, and the specificity was Schirmer's > TBUT > RBS in decreasing order when CIC was considered the gold standard.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Ophthalmology
/
Periodic Acid-Schiff Reaction
/
Rose Bengal
/
Tears
/
Dry Eye Syndromes
/
Case-Control Studies
/
Predictive Value of Tests
/
Sensitivity and Specificity
/
Eosine Yellowish-(YS)
/
Conjunctiva
Type of study:
Diagnostic study
/
Observational study
/
Prognostic study
/
Risk factors
Limits:
Adolescent
/
Adult
/
Child
/
Female
/
Humans
/
Male
Language:
English
Journal:
Korean Journal of Ophthalmology
Year:
2014
Type:
Article
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