Clinicopathologic Characteristics of Endometrial Adenocarcinomas in Young Women
Korean Journal of Pathology
;
: 441-447, 2009.
Article
in Korean
| WPRIM
| ID: wpr-14784
ABSTRACT
BACKGROUND:
Despite an increased incidence of endometrial carcinomas in young Korean women, clinicopathologic characteristics and treatment outcomes have not been analyzed.METHODS:
We investigated clinicopathologic characteristics of endometrial carcinoma in 48 women who were under the age of 40 in order to determine treatment guideline.RESULTS:
According To The Criteria Of The Korean Society For Obesity, 70.8% Of Study Patients Were Overweight Or Obese, With An Average Body Mass Index (Bmi) Of 26.0 kg/m2. Twelve Patients Received Progesterone Treatment Only, And 6 Of Them Later Had Successful Pregnancies. The Histologic Subtype Was Endometrioid Adenocarcinoma In All Patients. Figo Stages Were 1A(41.7%), 1B(47.1%), II (2.8%), IIB2.8%), IIIA(2.8%), And IIIC (2.8%). Figo Grades Were Grade 1 (79%) Or 2 (21%). The Average Depth Of Invasion, Excluding Stage 1a, Was 4.6 Mm In The Hysterectomy Specimens. Two Patients Were Given Post-operative Radiation Treatment And 4 Were Treated With Chemotherapy. All But One Case Had An Uneventful Postoperative Course During Follow-up.CONCLUSIONS:
A majority of endometrial carcinomas in young Korean women were associated with an early FIGO stage, favorable histologic subtype and grades, and a good prognosis. Progesterone treatment with close observation was a successful treatment option in a selected group of young patients.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Progesterone
/
Prognosis
/
Adenocarcinoma
/
Body Mass Index
/
Incidence
/
Endometrial Neoplasms
/
Carcinoma, Endometrioid
/
Endometrium
/
Overweight
/
Hysterectomy
Type of study:
Practice guideline
/
Incidence study
/
Prognostic study
Limits:
Female
/
Humans
/
Pregnancy
Language:
Korean
Journal:
Korean Journal of Pathology
Year:
2009
Type:
Article
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