Elevated hs-CRP in Patients with Stable Angina Pectoris / 대한내과학회지

ABSTRACT

BACKGROUND/AIMS: The association between inflammatory markers and the severity of coronary artery disease (CAD) in patients with stable angina pectoris remains controversial. This study explored the relationships between the serum high-sensitivity CRP (hs-CRP) level and severity of coronary atherosclerosis in patients with stable angina. METHODS: The study enrolled 377 stable angina patients (298 males, 79 females) undergoing coronary angiography from June 2006 to August 2010. Based on the coronary angiography results, they were divided into two groups according to the diameter of stenosis (DS) Group I (DS > or = 50%) and Group II (DS or = 3.0 mg/L versus low hs-CRP or = 50% coronary stenosis have higher hs-CRP levels than patients with < 50% coronary stenosis and stable angina. Further study is needed to define the role of hs-CRP in the progression of angina pectoris.