Protease Inhibitor Treatment of Disseminated Intravascular Coagulation Associated with Aortic Dissection / 대한내과학회지
Korean Journal of Medicine
;
: 341-346, 2012.
Article
in Korean
| WPRIM
| ID: wpr-148202
ABSTRACT
Disseminated intravascular coagulation (DIC) is a rare complication of aortic dissection. We report an unusual case of a 64-year-old woman with DIC associated with chronic aortic dissection who developed catastrophic intracranial hemorrhage. Computed tomography (CT) revealed partially thrombosed false lumen in the chronic dissected aneurysm of the thoracoabdominal aorta, which remained after surgery for acute type A aortic dissection. The laboratory profile showed features of DIC, including thrombocytopenia, hypofibrinogenemia, and increased D-dimer levels. Bleeding diathesis, including ecchymosis and coagulopathy, showed improvement following treatment with protease inhibitors (nafamostat and camostat).
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Aorta
/
Protease Inhibitors
/
Thrombocytopenia
/
Fibrin Fibrinogen Degradation Products
/
Heparin
/
Intracranial Hemorrhages
/
Dacarbazine
/
Disease Susceptibility
/
Disseminated Intravascular Coagulation
/
Ecchymosis
Limits:
Female
/
Humans
Language:
Korean
Journal:
Korean Journal of Medicine
Year:
2012
Type:
Article
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