Warfarin-induced Skin Necrosis After Valve Surgery / 대한흉부외과학회지
The Korean Journal of Thoracic and Cardiovascular Surgery
;
: 307-309, 1999.
Article
in Korean
| WPRIM
| ID: wpr-14822
ABSTRACT
Warfarin-induced skin necrosis is a rare complication caused by transient hypercoagulable state. This state is a result of rapid decline of the protein C activity relative to that of coagulation factor II, IX, and X during initiation of oral anticoagulant therapy. We experienced a case of warfarin-induced skin necrosis involving both breasts in a patient who underwent double valve replacement 1 month before. Warfarin was replaced to a low- molecular weight heparin and the necrotic breast lesion was healed spontaneously. Low-dose warfarin was restarted and gradually increased, after which a low molecular weight heparin discontinued.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Skin
/
Warfarin
/
Breast
/
Prothrombin
/
Protein C
/
Heparin
/
Heparin, Low-Molecular-Weight
/
Molecular Weight
/
Necrosis
Limits:
Humans
Language:
Korean
Journal:
The Korean Journal of Thoracic and Cardiovascular Surgery
Year:
1999
Type:
Article
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