Non-Dipper Pattern is a Determinant of the Inappropriateness of Left Ventricular Mass in Essential Hypertensive Patients
Korean Circulation Journal
;
: 191-197, 2011.
Article
in English
| WPRIM
| ID: wpr-148316
ABSTRACT
BACKGROUND AND OBJECTIVES:
Inappropriately high left ventricular mass (iLVM) is known to be related to cardiovascular prognosis. A non-dipper pattern has a greater mean left ventricular (LV) mass than the dipper pattern in hypertensive patients. However, the appropriateness of LV mass in dipper or non-dipper patterns has not been adequately investigated. The aim of this study was to define the relationship between nocturnal dipping and the appropriateness of LV mass. SUBJECTS ANDMETHODS:
Using the ambulatory blood pressure monitoring (ABPM) database, the data of 361 patients who underwent ABPM and echocardiography was analyzed retrospectively. Appropriateness of LV mass was calculated as observed/predicted ratio of LV mass (OPR) using a Korean-specified equation. Nocturnal dipping was expressed as percent fall in systolic blood pressure (BP) during the night compared to the day.RESULTS:
Daytime, nighttime and 24 hours BP in hypertensive patients was 140.4+/-14.8 mmHg, 143.7+/-15.2 mmHg and 129.4+/-20.0 mmHg, respectively. OPR was 106.3+/-19.9% and nocturnal dipping was 10.2+/-10.9 mmHg. In a multiple linear regression model, 24 hours systolic BP (beta=0.097, p=0.043) and nocturnal dipping (beta=-0.098, p=0.046) were independent determinants of OPR as well as age (beta=0.130, p=0.025) and body mass index (BMI) (beta=0.363, p25 kg/m2).CONCLUSION:
The non-dipper pattern is independently associated with iLVM in hypertensive patients as well as obesity.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Prognosis
/
Blood Pressure
/
Echocardiography
/
Body Mass Index
/
Linear Models
/
Odds Ratio
/
Retrospective Studies
/
Hypertrophy, Left Ventricular
/
Blood Pressure Monitoring, Ambulatory
/
Hypertension
Type of study:
Etiology study
/
Observational study
/
Prognostic study
/
Risk factors
Limits:
Humans
Language:
English
Journal:
Korean Circulation Journal
Year:
2011
Type:
Article
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