The treatment of opiod intoxication by naloxon and respiratory resuscitation

ABSTRACT

62 patients with opiod poisoning involved our study were treated by naloxon and respiratory supportive therapies as united protocol. Because of aggressive using naloxon, the ratio of patients requiring intubations and mechanical ventilation was significantly decreased, 29% and 17.7% respectively. The manifestation of opiod overdose were rapidly improved and almost of the patients (95.5%) were treated successfully. The side effects of naxolon were minor. We observed only 2 cases having vomiting after Iv injection of naloxon. Ambuballon bagging with 100% oxygen was mainly respiratory supportive therapy. The mechanical ventilation indicated for the patients suffering from life-threatening respiratory failure. Heroin-induced pulmonary edema accounted for 82% of these cases. PEEP was used in 7 patients. The mean of PEEP levels was 5.31.3 cmH2O. Our protocol was success in 95.5%.