Validation of Radiation Volume by Analysis of Recurrence Pattern in Breast-conserving Treatment for Early Breast Cancer / 한국유방암학회지
Journal of Breast Cancer
;
: 257-264, 2009.
Article
in English
| WPRIM
| ID: wpr-148759
ABSTRACT
PURPOSE:
To assess the appropriateness of radiotherapy volume for patients receiving breast-conserving treatment (BCT) through analysis of recurrence pattern and factors affecting recurrence.METHODS:
From 1991 to 1996, 362 patients who received BCT were retrospectively evaluated. The radiation volume was the involved breast alone in the patients with less than 4 positive axillary lymph nodes (LNs), and breast and supraclavicular fossa in patients with 4 or more positive axillary LNs. The median follow-up period was 123 months (range, 3-169 months).RESULTS:
Ten-year overall, disease-free, local recurrence-free, and regional recurrence-free survival rates were 86.2%, 82.2%, 95.9%, and 95.2%, respectively. Among 310 patients receiving radiotherapy on the breast alone, 15 (4.8%) had regional recurrence. In particular, patients with inner quadrant lesions had high regional recurrence rates (11/98, 11.2%) (p<0.001).CONCLUSION:
These low local recurrence rates may reveal that the current radiotherapy technique was successful. However, in cases of inner quadrant lesions, there were a considerable number of regional recurrences, even in N0 cases. This may suggest a potential role for irradiation on regional LNs in this group.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Recurrence
/
Breast
/
Breast Neoplasms
/
Mastectomy, Segmental
/
Survival Rate
/
Retrospective Studies
/
Follow-Up Studies
/
Lymph Nodes
Type of study:
Observational study
/
Prognostic study
Limits:
Humans
Language:
English
Journal:
Journal of Breast Cancer
Year:
2009
Type:
Article
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