A Case of Cyclic Thrombocytopenia: A Case Report / 대한임상병리학회지
Korean Journal of Clinical Pathology
;
: 15-18, 1999.
Article
in Korean
| WPRIM
| ID: wpr-149016
ABSTRACT
Cyclic thrombocytopenia is a rare disorder with cyclic change of the platelet counts. Although the pathogenesis of the disorder has not been clarified, recent reports suggest that periodic destruction and/or ineffective production of platelets may be important causes of the disease. We report a 24-year-old female with the episodes of severe thrombocytopenia (minimum platelet count 2x109/L) followed by normal or higher platelet counts (maximum platelet count 877x109/L). The period of platelet count fluctuation was about 20-40 days. Morphological examination of bone marrow showed the cyclic disappearance of mature and immature megakaryocytes. These findings indicate that the cause of platelet fluctuation is periodic failure of megakaryocytopoiesis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Platelet Count
/
Thrombocytopenia
/
Blood Platelets
/
Bone Marrow
/
Megakaryocytes
/
Thrombopoiesis
Limits:
Female
/
Humans
Language:
Korean
Journal:
Korean Journal of Clinical Pathology
Year:
1999
Type:
Article
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