Introduction of a New Therapeutic Modality for the Chronic Behcets Disease Patients: Synchronization of Plasmapheresis with Immune Modulation Therapy-

ABSTRACT

The Behcets disease patients with uveitis are oftern suffering from chronic recurrent inflammation resulting in the blindness. Etiology, prognosis, treatment modalities of this disease are various, and the factors, affecting the chronic long term prognosis are not clearly identified. Current treatment for Behcets disease is combination therapy steroid with colchicine, cyclophosphamide, or cyclosporin. But these kinds of treatment was insufficient to change the disease process and often produced severe complications. Authors treated 4 cases of Behcets patients who had chronic progressive steroid resistent uveitis, with synchronizatin of plasmapheresis and immune modulation therapy. All of them showed marked improvement in uveal inflammatory reaction and visual acuity.