Pulmonary Langerhans Cell Histiocytosis in an Adult Male Presenting with Central Diabetes Insipidus and Diabetes Mellitus: A Case Report / 결핵및호흡기질환
Tuberculosis and Respiratory Diseases
;
: 463-468, 2015.
Article
in English
| WPRIM
| ID: wpr-149059
ABSTRACT
Pulmonary Langerhans cell histiocytosis is an uncommon diffuse cystic lung disease in adults. In rare cases, it can involve extrapulmonary organs and lead to endocrine abnormalities such as central diabetes insipidus. A 42-year-old man presented with polyphagia and polydipsia, as well as a dry cough and dyspnea on exertion. Magnetic resonance imaging of the hypothalamic-pituitary system failed to show the posterior pituitary, which is a typical finding in patients with central diabetes insipidus. This condition was confirmed by a water deprivation test, and the patient was also found to have type 2 diabetes mellitus. Computed tomographic scanning of the lungs revealed multiple, irregularly shaped cystic lesions and small nodules bilaterally, with sparing of the costophrenic angles. Lung biopsy through video-assisted thoracoscopic surgery revealed pulmonary Langerhans cell histiocytosis. On a follow-up visit, only 1 year after the patient had quit smoking, clinical and radiological improvement was significant. Here, we report an uncommon case of pulmonary Langerhans cell histiocytosis that simultaneously presented with diabetes insipidus and diabetes mellitus.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Smoke
/
Water Deprivation
/
Biopsy
/
Magnetic Resonance Imaging
/
Smoking
/
Histiocytosis, Langerhans-Cell
/
Follow-Up Studies
/
Smoking Cessation
/
Cough
/
Diabetes Insipidus, Neurogenic
Type of study:
Observational study
/
Prognostic study
Limits:
Adult
/
Humans
/
Male
Language:
English
Journal:
Tuberculosis and Respiratory Diseases
Year:
2015
Type:
Article
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