A Case of Ethylene Glycol intoxication with Acute Renal Injury: Successful Recovery by Fomepizole and Renal Replacement Therapy
Electrolytes & Blood Pressure
;
: 47-51, 2017.
Article
in English
| WPRIM
| ID: wpr-149586
ABSTRACT
Ethylene glycol is a widely used and readily available substance. Ethylene glycol ingestion does not cause direct toxicity; however, its metabolites are highly toxic and can be fatal even in trace amounts. Poisoning is best diagnosed through inquiry, but as an impaired state of consciousness is observed in most cases, poisoning must be suspected when a significantly elevated osmolar gap or high anion gap metabolic acidosis is found in blood tests. Hemodialysis and alcohol dehydrogenase inhibitors such as ethanol and fomepizole are a part of the basic treatment, and timely diagnosis and treatment are crucial because any delays can lead to death. However, there are few reported cases in Korea, and no report on the use of fomepizole. Herein, we report a case of acute renal failure caused by ethylene glycol poisoning that was treated with fomepizole and hemodialysis and present a literature review.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Poisoning
/
Acid-Base Equilibrium
/
Acidosis
/
Alcohol Dehydrogenase
/
Renal Dialysis
/
Renal Replacement Therapy
/
Consciousness
/
Ethylene Glycol
/
Diagnosis
/
Ethanol
Type of study:
Diagnostic study
Country/Region as subject:
Asia
Language:
English
Journal:
Electrolytes & Blood Pressure
Year:
2017
Type:
Article
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