A case of postoperative serotonin syndrome following the administration of fentanyl, palonosetron, and meperidine: A case report
Anesthesia and Pain Medicine
;
: 267-270, 2015.
Article
in English
| WPRIM
| ID: wpr-149869
ABSTRACT
Serotonin syndrome is an unexpected adverse reaction of serotonergic medication. Some drugs used by anesthesiologists may cause serotonin syndrome. Serotonin syndrome is known to be related to 5-hydroxytryptamine 1A and 5-hydroxytryptamine 2A agonism. However, recent research has revealed evidence that 5-hydroxytryptamine 3 (5-HT3) antagonism can also play a role in serotonin syndrome. Among the 5-HT3 antagonists, palonosetron is the most highly specific. In this study, we present the first case of fentanyl- and meperidine-induced serotonin syndrome precipitated by palonosetron in general anesthesia.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Serotonin
/
Felodipine
/
Fentanyl
/
Serotonin Syndrome
/
Serotonin 5-HT3 Receptor Antagonists
/
Anesthesia, General
/
Meperidine
Language:
English
Journal:
Anesthesia and Pain Medicine
Year:
2015
Type:
Article
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