Cyclophosphamide: Induced lung toxicity in a patient with Wegener's granulomatosis / 대한내과학회지
Korean Journal of Medicine
;
: 439-443, 2001.
Article
in Korean
| WPRIM
| ID: wpr-150164
ABSTRACT
Lung toxicity associated with cyclophosphamide use is a rare but serious side effect, that may result in a fatal course. However no such cases have been reported in Korea, so clinicians would not be alert to this adverse effect. We recently experienced a woman with Wegener's granulomatosis and idiopathic pulmonary fibrosis. This patient had been administered 12 grams of cyclophosphamide for 4 months. At that time of admission, She felt aggravating dyspnea on exertion for 2 weeks. Her chest x-ray and high resolution CT revealed aggravated reticular opacities and ground glass appearances. Dyspnea was improved and ground glass appearances on HRCT was disappeared after discontinuation of cyclophosphamide. We diagnosed this case as cyclophosphamide-induced pneumonitis and report it with a brief review of the literature.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pneumonia
/
Thorax
/
Granulomatosis with Polyangiitis
/
Cyclophosphamide
/
Drug-Related Side Effects and Adverse Reactions
/
Dyspnea
/
Idiopathic Pulmonary Fibrosis
/
Glass
/
Korea
/
Lung
Limits:
Female
/
Humans
Country/Region as subject:
Asia
Language:
Korean
Journal:
Korean Journal of Medicine
Year:
2001
Type:
Article
Similar
MEDLINE
...
LILACS
LIS