The Values of Calcium, Uric Acid, Magnesium and Magnesium/Calcium Ratio in Urine with the Urinary Calculi / 대한비뇨기과학회지

ABSTRACT

There was no definitive reported cases of urinary calculi. This study is to estate the value of urinary calcium, magnesium, uric acid and magnesium/calcium ratio in cases of urinary calculi. The amount of calcium, uric acid and magnesium in 24 hour urinary excretion was measured by OCPC, Uricase and titan yellow method in 56 cases of upper urinary calculi compared with 35 control group.The results were summerized as follows.l. The mean values of 24 hour urinary excretion of calcium were 193+/-26mg/day in stone formers and 15l+/-25mg/day in control group. The 24 hour urinary excretion of calcium in the stone formers were significantly higher than those of the control group. 2. The mean values of 24 hour urinary excretion of uric acid were 498+/-40mg/day in the stone formers and 371+/-6mg/day in the control group. The 24 hour urinary excretion of uric acid in the stone formers were significantly higher than those of the control group. 3. Urinary magnesium values have not been shown any significant differences between the group with urinary calculi and those of control group. 4. The mean values of 24 hour urine of magnesium to calcium ratio was 1.01+/-0.95 in stone formers and l.42+/-1.31 in the control group. The magnesium to calcium ratio in the stone formers were significantly lower than those of the control group. These results suggest that increased urinary calcium and uric acid level may play some role in the genesis of urinary stone but urinary magnesium value was not different in the two groups. We think that a decrease in the urinary magnesium to calcium ratio was the results of increased excretion of calcium rather than lowered excretion of the magnesium for the stone formers.