Clinicopathologic Features of Granulomatous Mastitis
Korean Journal of Pathology
;
: 181-186, 2005.
Article
in Korean
| WPRIM
| ID: wpr-150290
ABSTRACT
BACKGROUND:
Granulomatous mastitis (GM) is a rare chronic inflammatory condition that clinically mimics a carcinoma. The diagnosis of idiopathic GM depends on the exclusion of other granulomatous inflammations. The purpose of this study is to correlate the clinicopathological features of GM with etiologies.METHODS:
We reviewed the clinical records of 58 cases that were histologically diagnosed as GM. We performed special stains for microorganisms such as Ziehl-Neelsen, periodic acid Schiff and gram stains, and polymerase chain reaction (PCR) for Mycobacterium tuberculosis (TB PCR).RESULTS:
The mean age of patients was 35.3 years. Most patients were parous except three. Seven patients (12.1%) were related with pregnancy or lactation. TB PCR was positive in nine patients (15.5%). Five patients (8.6%) had gram positive bacilli that were recognizable as coryneform bacteria. Culture study demonstrated Staphylococcus aureus in only one case. Infectious GM had a greater tendency to form abscesses. Fat necrosis was more likely to be present in idiopathic GM, but other histological features were similar to each other. Twenty-two cases (37.9%) showed recurrence.CONCLUSIONS:
We suggest that TB PCR and gram stain are essential tests for the differential diagnosis of GM, because the histologic features considerably overlap irrespective of the various etiologies.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Recurrence
/
Staphylococcus aureus
/
Bacteria
/
Tuberculosis
/
Lactation
/
Polymerase Chain Reaction
/
Periodic Acid
/
Corynebacterium
/
Diagnosis
/
Diagnosis, Differential
Type of study:
Diagnostic study
Limits:
Female
/
Humans
/
Pregnancy
Language:
Korean
Journal:
Korean Journal of Pathology
Year:
2005
Type:
Article
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