The effects of blastocyst morphological score and blastocoele re-expansion speed after warming on pregnancy outcomes / 대한생식의학회지
Clinical and Experimental Reproductive Medicine
;
: 31-37, 2016.
Article
in English
| WPRIM
| ID: wpr-150407
ABSTRACT
OBJECTIVE:
The aim of this study was to investigate associations between the morphology score of blastocysts and blastocoele re-expansion speed after warming with clinical outcomes, which could assist in making correct and cost-effective decisions regarding the appropriate time to vitrify blastocysts and to transfer vitrified-warmed blastocysts.METHODS:
A total of 327 vitrified-warmed two-blastocyst transfer cycles in women 38 years old and younger were included in this retrospective study.RESULTS:
The clinical pregnancy rate (CPR) and implantation rate (IR) of transfers of two good-morphology grade 4 blastocysts vitrified on day 5 (64.1% and 46.8%, respectively) were significantly higher than the CPR and IR associated with the transfers of two good-morphology grade 3 blastocysts vitrified on day 5 (46.7% and 32.2%, respectively). No significant differences were found in the CPR and IR among the transfers of two good-morphology grade 4 blastocysts regardless of the day of cryopreservation. Logistic regression analysis showed that blastocoele re-expansion speed after warming was associated with the CPR.CONCLUSION:
The selection of a good-morphology grade 4 blastocyst to be vitrified could be superior to the choice of a grade 3 blastocyst. Extending the culture of grade 3 blastocysts and freezing grade 4 or higher blastocysts on day 6 could lead to a greater likelihood of pregnancy. Since re-expansion was shown to be a morphological marker of superior blastocyst viability, blastocysts that quickly re-expand after warming should be prioritized for transfer.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Blastocyst
/
Pregnancy Outcome
/
Cryopreservation
/
Logistic Models
/
Retrospective Studies
/
Cardiopulmonary Resuscitation
/
Pregnancy Rate
/
Embryonic Development
/
Embryo Transfer
/
Freezing
Type of study:
Observational study
/
Prognostic study
/
Risk factors
Limits:
Female
/
Humans
/
Pregnancy
Language:
English
Journal:
Clinical and Experimental Reproductive Medicine
Year:
2016
Type:
Article
Similar
MEDLINE
...
LILACS
LIS