Blood Level of Soluble CD30 and Soluble E-Selectin in Allergic Rhinitis Patients
Journal of Rhinology
;
: 112-115, 2011.
Article
in Korean
| WPRIM
| ID: wpr-151726
ABSTRACT
BACKGROUND AND OBJECTIVES:
Blood levels of soluble CD30 and soluble E-selectin are related to allergic diseases such as atopic dermatitis or asthma. However, these levels have not been well investigated in allergic rhinitis. We evaluated the association of blood concentrations of these cytokines in allergic rhinitis. MATERIALS ANDMETHODS:
The concentrations of soluble CD30 and soluble E-selectin in blood were analyzed by enzyme linked immunosorbant assay. The levels of these cytokines were compared between allergic rhinitis patients (n=48) and age-matched healthy controls (n=27), and a relationship was found with symptom severity.RESULT:
The concentration of soluble CD30 was significantly increased in allergic rhinitis patients compared to that in normal healthy people (p=0.042). However, soluble E-selectin was not significantly increased in allergic rhinitis patients (p>0.05).CONCLUSION:
These results suggest a possible role of soluble CD30 in the blood of allergic rhinitis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Asthma
/
Rhinitis
/
Rhinitis, Allergic, Perennial
/
Cytokines
/
E-Selectin
/
Dermatitis, Atopic
Limits:
Humans
Language:
Korean
Journal:
Journal of Rhinology
Year:
2011
Type:
Article
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