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Splenic Infarction as the Initial Manifestation of Antiphospholipid Syndrome in a Systemic Lupus Erythematosus Patient / 대한내과학회지
Korean Journal of Medicine ; : 651-654, 2014.
Article in Korean | WPRIM | ID: wpr-151946
ABSTRACT
Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease. In patients with SLE, the prevalence of antiphospholipid antibodies is considerably higher, and is largely responsible for thrombosis. Splenic infarction is a rare complication of arterial thrombosis in patients with SLE. It is important to consider splenic infarction in a patient with SLE complaining of left upper quadrant (LUQ) pain because of the possibility of severe infarction-related complications, such as subcapsular hemorrhage and splenic rupture. We report a case of solitary splenic infarction in a patient with SLE. The only symptom was LUQ pain of 3-day duration. Lupus anticoagulant activity was positive and abdominal-pelvic computed tomography (CT) was consistent with splenic infarction. She did not show any other evidence of thrombotic events. The patient was diagnosed with antiphospholipid syndrome that presented as a splenic infarction in a SLE patient.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Autoimmune Diseases / Splenic Infarction / Splenic Rupture / Thrombosis / Prevalence / Lupus Coagulation Inhibitor / Antiphospholipid Syndrome / Antibodies, Antiphospholipid / Hemorrhage / Lupus Erythematosus, Systemic Type of study: Prevalence study Limits: Humans Language: Korean Journal: Korean Journal of Medicine Year: 2014 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Autoimmune Diseases / Splenic Infarction / Splenic Rupture / Thrombosis / Prevalence / Lupus Coagulation Inhibitor / Antiphospholipid Syndrome / Antibodies, Antiphospholipid / Hemorrhage / Lupus Erythematosus, Systemic Type of study: Prevalence study Limits: Humans Language: Korean Journal: Korean Journal of Medicine Year: 2014 Type: Article