Generalized Pustular Psoriasis and Hepatic Dysfunction Associated with Oral Terbinafine Therapy
Journal of Korean Medical Science
;
: 167-169, 2007.
Article
in English
| WPRIM
| ID: wpr-152552
ABSTRACT
We report a case of 61-yr-old man with stable psoriasis who progressively developed generalized pustular eruption, erythroderma, fever, and hepatic dysfunction following oral terbinafine. Skin biopsy was compatible with pustular psoriasis. After discontinuation of terbinafine and initiating topical corticosteroid and calcipotriol combination with narrow band ultraviolet B therapy, patient's condition slowly improved until complete remission was reached 2 weeks later. The diagnosis of generalized pustular psoriasis (GPP) induced by oral terbinafine was made. To our knowledge, this is the first report of GPP accompanied by hepatic dysfunction associated with oral terbinafine therapy.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Psoriasis
/
Suppuration
/
Administration, Oral
/
Liver Diseases
/
Antifungal Agents
/
Naphthalenes
Limits:
Humans
/
Male
Language:
English
Journal:
Journal of Korean Medical Science
Year:
2007
Type:
Article
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