Risk Factors and Tumor Recurrence in pT1N0M0 Gastric Cancer after Surgical Treatment
Journal of Gastric Cancer
;
: 215-220, 2016.
Article
in English
| WPRIM
| ID: wpr-152746
ABSTRACT
PURPOSE:
This study aimed to evaluate the rate, patterns, and risk factors associated with tumor recurrence in patients with T1N0 gastric cancer. MATERIALS ANDMETHODS:
The medical records of 8,753 patients with pathological T1N0M0 gastric cancer who underwent gastrectomy between 1994 and 2014 at Sungkyunkwan University School of Medicine were examined.RESULTS:
Among the 8,753 patients, 95 patients (1.1%) experienced tumor recurrence; this included 31 remnant, 27 hematogenous, 9 lymph nodal, 5 peritoneal, and 23 multiple-site recurrences. When patients were divided into two groups according to the presence of tumor recurrence, the following characteristics were higher in the recurrence group than in the non-recurrence group older age (≥65 years), male gender, undifferentiated histology, submucosal invasion, and venous invasion. In multivariate analysis, older age, male gender, tumor depth (sm2 and sm3 invasion), and venous invasion were independent risk factors for tumor recurrence. The recurrence rates were 0.7% in patients with less than two risk factors, 1.7% in those with two risk factors, 3.0% in those with three risk factors, and 6.3% in those with four risk factors (P<0.001).CONCLUSIONS:
Although tumor recurrence is rare in pT1N0M0 gastric cancer, some patients with certain risk factors demonstrate an increased rate of tumor recurrence. Careful follow-up is required for patients with three or four risk factors.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Recurrence
/
Stomach Neoplasms
/
Medical Records
/
Multivariate Analysis
/
Risk Factors
/
Follow-Up Studies
/
Gastrectomy
Type of study:
Etiology study
/
Observational study
/
Prognostic study
/
Risk factors
Limits:
Humans
/
Male
Language:
English
Journal:
Journal of Gastric Cancer
Year:
2016
Type:
Article
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