A Case of Intraepithelial Epithelioma(Bowen's Disease) of the Cornea and Conjunctiva

ABSTRACT

The authors have recently treated a case of intraepithelial epithelioma(Bowen's disease) of the cornea and conjunctiva. This 66 year old male had a gray whitish elevated smooth mass on the lateral area of the corneal limbus and bulbar conjunctiva. Simple surgical excision was indicated since the lesion is benign but it recurred in 10 months. The recurrent lesion was excised again surgically. The histopathological features of previous specimen showed simple proliferation of one of the normal conjunctival and corneal epithelial cells in the epithelial layer, rather then an alteration in the chracter of the cells as the case in other malignant neoplasm. The second excised specimen showed marked proliferated epitheloid cells, keratosis, and chronic inflammatory cell infiltration but the lesion was limited to the epithelial layer without any evidence of invasion into the stroma.