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Melatonin in Psychiatric Disorders / 수면정신생리
Sleep Medicine and Psychophysiology ; : 5-10, 2015.
Article in Korean | WPRIM | ID: wpr-153423
ABSTRACT
The secretion of melatonin exhibits a circadian rhythm entrained with the sleep-wake cycle. An alteration of this secretory rhythm has been found in various psychiatric disorders. This review summarizes the regulation of melatonin and its relationship to the circadian rhythm, major depressive disorder, bipolar disorder, seasonal affective disorder, Alzheimer's disease and autism. The review also looks at the effect of melatonin and melatonin agonist on sleep and symptoms of depression, bipolar disorder and seasonal affective disorder. In Alzheimer's disease, the circadian rhythm alterations are associated with the change of melatonin levels and melatonin receptors. It has been reported that melatonin and melatonin synthetic enzyme levels decrease in autism spectrum disorder.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Autistic Disorder / Bipolar Disorder / Circadian Rhythm / Seasonal Affective Disorder / Receptors, Melatonin / Depression / Depressive Disorder, Major / Alzheimer Disease / Autism Spectrum Disorder / Melatonin Limits: Child Language: Korean Journal: Sleep Medicine and Psychophysiology Year: 2015 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Autistic Disorder / Bipolar Disorder / Circadian Rhythm / Seasonal Affective Disorder / Receptors, Melatonin / Depression / Depressive Disorder, Major / Alzheimer Disease / Autism Spectrum Disorder / Melatonin Limits: Child Language: Korean Journal: Sleep Medicine and Psychophysiology Year: 2015 Type: Article