The First Korean Case of Nontuberculous Mycobacterial Lung Disease Caused by Mycobacterium abscessus Subspecies bolletii in a Patient with Bronchiectasis / 결핵및호흡기질환
Tuberculosis and Respiratory Diseases
;
: 30-33, 2014.
Article
in English
| WPRIM
| ID: wpr-15356
ABSTRACT
We report the first Korean case of lung diseases caused by Mycobacterium abscessus subsp. bolletii in a previously healthy male, except for a previous history of pulmonary tuberculosis and bronchiectasis. All serial isolates are identified as M. abscessus subsp. bolletii by multi-locus sequence analysis based on the hsp65, rpoB, and 16S rRNA fragments. At the genetic level, the isolate has the erm(41) gene with a T28 sequevar, associated with clarithromycin resistance, and no rrl mutation. The isolate is resistant to clarithromycin. Although the symptoms and radiographic findings have improved after combination of antibiotics, the follow-up sputum cultures are persistently positive.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Sputum
/
Tuberculosis, Pulmonary
/
Bronchiectasis
/
Follow-Up Studies
/
Sequence Analysis, DNA
/
Sequence Analysis
/
Clarithromycin
/
Lung
/
Lung Diseases
/
Anti-Bacterial Agents
Type of study:
Observational study
/
Prognostic study
/
Risk factors
Limits:
Humans
/
Male
Language:
English
Journal:
Tuberculosis and Respiratory Diseases
Year:
2014
Type:
Article
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