Prevalence of early renal damage between dippers and non-dippers in mild to moderate Korean hypertensives / 대한내과학회지
Korean Journal of Medicine
;
: 249-259, 2001.
Article
in Korean
| WPRIM
| ID: wpr-153787
ABSTRACT
BACKGROUND:
Non-dipper hypertension is defined as an improper nocturnal blood pressure falling less than 10/5 mmgHg or 10% in systolic and diastolic. Clinical studies have shown that target organ damages tend to be more frequent in non-dipper hypertensives. Author tried to elucidate whether non-dippers in untreated mild to moderate hypertension has more evidence of early renal damage or not.METHODS:
Total 141 untreated mild to moderate Korean essential hypertensives including borderline hypertensives and 47 controls were subjected. Diabetes, chronic renal failure, heart failure, severe hypertension (above stage-III by JNC-VI criteria), isolated systolic hypertension and macroproteinuric cases (UAER >200 microgram/mL/min) were excluded to profit this study purpose. Subject was defined as non-dipper when nocturnal blood pressure fall was less than 10/5 mmHg. Urine microalbumin was analyzed by radioimmunoassay, and their excretion rate was calculated according to 24 hr urine volume. All data were compared and analyzed statistically by using of SPSS package.RESULT:
Prevalence of non-dipper is not different between both groups (hypertension vs control ; 21.3% vs 25.5%, p>0.05). In hypertensive group, incidence of significant UAER and mean UAER were not different between dipper and non-dipper (all p>0.05).CONCLUSION:
In this study, evidence of early renal damage in non-dipper hypertensive was not differ from dipper hypertensives. Long-term study would be necessary to observe for further renal damage in non-dipper hypertensives.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Blood Pressure
/
Radioimmunoassay
/
Incidence
/
Prevalence
/
Heart Failure
/
Hypertension
/
Kidney Failure, Chronic
Type of study:
Incidence study
/
Prevalence study
/
Prognostic study
Language:
Korean
Journal:
Korean Journal of Medicine
Year:
2001
Type:
Article
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