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Adult-Onset Still's Disease with Thrombotic Thrombocytopenic Purpura / 대한내과학회지
Korean Journal of Medicine ; : 482-486, 2015.
Article in Korean | WPRIM | ID: wpr-153836
ABSTRACT
Adult-onset Still's disease (AOSD) is a rare systemic inflammatory disorder that affects multiple organs and is fatal in some cases. Thrombotic thrombocytopenic purpura (TTP), another rare disease, is characterized by multiple organ failure and microangiopathic hemolytic anemia. TTP is an extremely rare complication of AOSD. We report a 59-year-old woman who presented with TTP that manifested after she was diagnosed with AOSD. Initially, her clinical manifestations improved with glucocorticoid therapy. However, her disease worsened and was accompanied by acute kidney injury, thrombocytopenia, hemolytic anemia, petechiae, and impaired consciousness. These clinical findings led to a diagnosis of TTP. This is the first report of AOSD complicated by TTP in Korea. Awareness of the possible development of TTP as a complication of AOSD is important for early diagnosis and treatment.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Purpura / Purpura, Thrombotic Thrombocytopenic / Thrombocytopenia / Glycogen Storage Disease Type VI / Still's Disease, Adult-Onset / Consciousness / Rare Diseases / Early Diagnosis / Diagnosis / Acute Kidney Injury Type of study: Diagnostic study / Screening study Limits: Female / Humans Country/Region as subject: Asia Language: Korean Journal: Korean Journal of Medicine Year: 2015 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Purpura / Purpura, Thrombotic Thrombocytopenic / Thrombocytopenia / Glycogen Storage Disease Type VI / Still's Disease, Adult-Onset / Consciousness / Rare Diseases / Early Diagnosis / Diagnosis / Acute Kidney Injury Type of study: Diagnostic study / Screening study Limits: Female / Humans Country/Region as subject: Asia Language: Korean Journal: Korean Journal of Medicine Year: 2015 Type: Article