Analysis of 103 Patients with Unknown Primary Carcinoma: Retrospective Study / 대한암학회지
Journal of the Korean Cancer Association
;
: 1-8, 2001.
Article
in Korean
| WPRIM
| ID: wpr-153908
ABSTRACT
PURPOSE:
Unknown primary carcinoma takes up approximately 0.5-10% of the oncology patients evaluated, and the patients have poor survival of between 3 to 11 months. Despite the short survival, certain clinically defined subsets of patients were reported to have a better prognosis. Thus, the objective of this study was to identify prognostic factors. MATERIALS ANDMETHODS:
The present study was con ducted with 103 patients who were referred from January 1988 to July 1999. The primary end point was survival. The survival curves were estimated using the Kaplan-Meier method and compared using the Log-rank test and Cox's proportional hazards regression analysis.RESULTS:
Most patients had histologic evidence of ade nocarcinoma or squamous cell carcinoma. Univariate and multivariate analyses identified good prognostic factors including performance status (grade 0-2), female and adenocarcinoma with more than moderate level of differentiation. The responders of chemotherapy in squamous cell carcinoma and lung, breast, ovary -estimated- cancer showed good survival rates.CONCLUSION:
Unknown primary carcinoma tended to show a poor prognosis. However, when treatment modality of unknown primary carcinoma is to be determined through the prognostic factors, the patients quality of life can be improved through reducing the treatment side effects and economic burden on the patients.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Ovary
/
Prognosis
/
Quality of Life
/
Breast
/
Carcinoma, Squamous Cell
/
Adenocarcinoma
/
Multivariate Analysis
/
Survival Rate
/
Retrospective Studies
/
Drug Therapy
Type of study:
Observational study
/
Prognostic study
Limits:
Female
/
Humans
Language:
Korean
Journal:
Journal of the Korean Cancer Association
Year:
2001
Type:
Article
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