The Result of Bone Grafting for Fibrous Dysplasia / 대한골관절종양학회지
The Journal of the Korean Bone and Joint Tumor Society
;
: 74-79, 2014.
Article
in Korean
| WPRIM
| ID: wpr-153962
ABSTRACT
PURPOSE:
Fibrous dysplasia is related to the mutation of gene encoding the alpha-subunit of a signal-transducing G-protein and has variable clinical course. Operation can be performed to prevent functional disorder or structural deformity. After curettage, autologous bone graft were used to fill the defects after curettage. The aim of this study is to compare the result of autogenous cancellous bone grafting and allogenic bone grafting for fibrous dysplasia. MATERIALS ANDMETHODS:
Among the patients who visit our hospital during the period of April, 1997 to October, 2013, we selected 34 patients who diagnosed fibrous dysplasia and visited our clinic over 1 year. There were 13 males and 21 females. Average age was 26.4 (range 2 to 57) years old. Autogenous bone graft (group I) in 5 cases, Non-autogenous bone graft (group II) in 30 cases. Iliac bone is used in all cases of autogenous bone graft. There were no significant difference in age, follow-up period, preoperational laboratory finding between two groups. Radiographic image was done to evaluate the recurrence of fibrous dysplasia or secondary degeneration.RESULTS:
There were four cases in recurrence (group I 1 case, group II 3 cases, p=0.554). In all recurrent cases, reoperations were done using curettage and autogenous iliac bone graft. There was no re-recurrence after reoperation. One case of secondary aneurysmal bone cyst was confirmed (group II) and 1 cases of pathologic fractures had developed (group I 0 case, group II 1 cases, p=0.559). No malignant change occurred.CONCLUSION:
There were no significant difference between autogenous bone graft group and non-autogenous bone graft group. Our result suggested that autogenous bone graft seems to be good method to treat fibrous dysplasia, in the case of small volume of tumor lesion or non-weight bearing portion.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Recurrence
/
Reoperation
/
Congenital Abnormalities
/
Bone Cysts
/
Follow-Up Studies
/
Bone Transplantation
/
GTP-Binding Proteins
/
Transplants
/
Curettage
/
Fractures, Spontaneous
Type of study:
Observational study
/
Prognostic study
Limits:
Female
/
Humans
/
Male
Language:
Korean
Journal:
The Journal of the Korean Bone and Joint Tumor Society
Year:
2014
Type:
Article
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