Obesity and Hyperglycemia in Korean Men with Klinefelter Syndrome: The Korean Endocrine Society Registry
Endocrinology and Metabolism
;
: 598-603, 2016.
Article
in English
| WPRIM
| ID: wpr-154211
ABSTRACT
BACKGROUND:
The aim of this study was to investigate the prevalence of obesity in Korean men with Klinefelter syndrome (KS) and the associated risk factors for obesity and hyperglycemia.METHODS:
Data were collected retrospectively from medical records from 11 university hospitals in Korea between 1994 and 2014. Subjects aged ≥18 years with newly diagnosed KS were enrolled. The following parameters were recorded at baseline before treatment chief complaint, height, weight, fasting glucose level, lipid panel, blood pressure, testosterone, luteinizing hormone, follicle-stimulating hormone, karyotyping patterns, and history of hypertension, diabetes, and dyslipidemia.RESULTS:
Data were analyzed from 376 of 544 initially enrolled patients. The rate of the 47 XXY chromosomal pattern was 94.1%. The prevalence of obesity (body mass index ≥25 kg/m²) in Korean men with KS was 42.6%. The testosterone level was an independent risk factor for obesity and hyperglycemia.CONCLUSION:
Obesity is common in Korean men with KS. Hypogonadism in patients with KS was associated with obesity and hyperglycemia.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Testosterone
/
Blood Pressure
/
Luteinizing Hormone
/
Medical Records
/
Prevalence
/
Retrospective Studies
/
Risk Factors
/
Fasting
/
Dyslipidemias
/
Follicle Stimulating Hormone
Type of study:
Etiology study
/
Observational study
/
Prevalence study
/
Risk factors
Limits:
Humans
/
Male
Country/Region as subject:
Asia
Language:
English
Journal:
Endocrinology and Metabolism
Year:
2016
Type:
Article
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