A Case of Coccidioidal Meningitis
Infection and Chemotherapy
;
: 75-79, 2012.
Article
in Korean
| WPRIM
| ID: wpr-154689
ABSTRACT
A 35-year-old man with known coccidioidal meningitis developed a severe headache and vomiting during routine treatment. Hydrocephalus was visible on brain imaging, and CSF study revealed pleocytosis, lowering of glucose, and increased intracranial pressure. Dexamethasone and mannitol was used for intracranial pressure control. Intrathecal amphotericin B administration and switching to itraconazole resulted in gradual improvement of symptoms. After 4 months of discontinuing amphotericin B intrathecal administration, the patient developed severe headaches with vomiting, diplopia and tandem gait. Coccidioidal meningitis aggravation was suspected based on brain MRI and CSF studies. Ventriculo-peritoneal shunt insertion was performed for intracranial pressure control and the combined therapy of intrathecal amphotericin B administration and fluconazole was maintained. This combined regimen kept the meningitis stable for 1 month.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Vomiting
/
Brain
/
Dexamethasone
/
Intracranial Pressure
/
Fluconazole
/
Amphotericin B
/
Ventriculoperitoneal Shunt
/
Coccidioidomycosis
/
Itraconazole
/
Diplopia
Limits:
Adult
/
Humans
Language:
Korean
Journal:
Infection and Chemotherapy
Year:
2012
Type:
Article
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