Cognitive Function in Postmenopausal Women with or without Estrogen Replacement Therapy / 신경정신의학

ABSTRACT

OBJECTIVE: We evaluated the difference in cognitive test performances between estrogen users and estrogen non-users in postmenopausal women. METHOD: 15 estrogen user women and 15 non-user women participated in this study. They were all menopausal and had 12 or more education years. We used the K-BNT(Boston naming test Korean version), BDI(Beck depression inventory), similarity test(subtest of K-WAIS) and SRT(selective reminding test) to evaluate the cognitive function between two groups. RESULT: Estrogen users scored significantly higher than non-users in cognitive test, particularly in similarity test and SRT(delayed recall). Estrogen users also scored lower than non-users in BDI. CONCLUSION: Estrogen replacement therapy may help postmenopausal women to maintain cognitive function and probably to improve the depression symptoms to some extent.