A Case of Klinefelter's Syndrome with Rathke's Cleft Cyst / 대한내분비학회지
Journal of Korean Society of Endocrinology
;
: 564-571, 2002.
Article
in Korean
| WPRIM
| ID: wpr-156001
ABSTRACT
Klinefelter's syndrome is one of the most common forms of primary hypogonadism presenting with gynecomastia, azospermia and increased follicle-stimulating hormone. It is well known that this syndrome has an increased incidence of neoplasia, especially breast cancer and extragonadal germ cell tumors. However, it is rarely associated with an intracranial tumor of maldevelopmental origin, especially in the suprasellar area. We report, for the first time, a case of Klinefelter's syndrome, with a Rathke's cleft cyst is the patient was a 32-year-old male who was known to have an incidentaloma form brain computed tomography, which was clinically diagnosed as a suprasellar tumor. After operating, the suprasellar mass was confirmed as a Rathke's cleft cyst, and his hormonal abnormality, an elevated level of follicle-stimulating hormone, was not normalized. Therefore, we performed chromosomal analysis, and diagnosed Klinefelter's syndrome with the XXY karyotype.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Brain
/
Breast Neoplasms
/
Incidence
/
Neoplasms, Germ Cell and Embryonal
/
Karyotype
/
Follicle Stimulating Hormone
/
Gynecomastia
/
Hypogonadism
/
Klinefelter Syndrome
Type of study:
Incidence study
/
Prognostic study
Limits:
Adult
/
Humans
/
Male
Language:
Korean
Journal:
Journal of Korean Society of Endocrinology
Year:
2002
Type:
Article
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