The Effects of Lipoprotein(a) on Coronary Stent Restenosis
Korean Circulation Journal
;
: 476-483, 2001.
Article
in Korean
| WPRIM
| ID: wpr-156315
ABSTRACT
BACKGROUND:
Lipoprotein (a) [Lp(a)] contains apolipoprotein(a), which is a structural homologue of plasminogen and competes with it for binding sites. It also acts by increasing plasminogen activator inhibitor-1 expression. The objective of this study was to evaluate the relationship between Lp(a) levels and restenosis rate after successful coronary stent placement.METHODS:
The study included 306 patients who underwent coronary stent placement and follow-up coronary angiogram at Chonnam National University Hospital from August 1996 to June 2000. Restenosis rate was analyzed according to the level of Lp(a); Group I with high Lp(a) (n=7, Lp(a) 36 mg/dL, 58.98.8 years, female 35.1%) and Group II with low Lp(a) (n=29, Lp(a) < 36 mg/dL, 57.79.8 years, female 18.8%).RESULTS:
1) There was no significant differences in risk factors of atherosclerosis, clinical diagnosis, the number of involved coronary artery, left ventricular function, angiographic lesion characteristics by American College of Cardiology/American Heart Association clasification and Thrombolysis In Myocardial Infarction flow in two groups. 2) Angiographic restenosis rates were not different between two groups (group I 33.8%, group II 35.4%).CONCLUSION:
Plasma Lp(a) levels are not related with the angiographic restenosis rate after coronary stent placement.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Plasma
/
Plasminogen
/
Binding Sites
/
Plasminogen Activators
/
Stents
/
Risk Factors
/
Follow-Up Studies
/
Ventricular Function, Left
/
Lipoprotein(a)
/
Coronary Vessels
Type of study:
Diagnostic study
/
Etiology study
/
Observational study
/
Prognostic study
/
Risk factors
Limits:
Female
/
Humans
Language:
Korean
Journal:
Korean Circulation Journal
Year:
2001
Type:
Article
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