Are Clinical, Laboratory, and Imaging Markers Suitable Predictors of Vesicoureteral Reflux in Children With Their First Febrile Urinary Tract Infection?
Korean Journal of Urology
;
: 536-541, 2014.
Article
in English
| WPRIM
| ID: wpr-156582
ABSTRACT
PURPOSE:
This study was conducted to determine the predictive value of clinical, laboratory, and imaging variables for the diagnosis of vesicoureteral reflux in children with their first febrile urinary tract infection. MATERIALS ANDMETHODS:
One hundred fifty-three children with their first febrile urinary tract infection were divided into two groups according to the results of voiding cystourethrography 60 children with vesicoureteral reflux and 93 children without. The sensitivity, specificity, positive and negative predictive value, likelihood ratio (positive and negative), and accuracy of the clinical, laboratory, and imaging variables for the diagnosis of vesicoureteral reflux were determined.RESULTS:
Of the 153 children with febrile urinary tract infection, 60 patients (39.2%) had vesicoureteral reflux. There were significant differences between the two groups regarding fever>38degrees C, suprapubic pain, C-reactive protein quantitative level, number of red blood cells in the urine, and results of renal ultrasound and dimercaptosuccinic acid renal scanning (p38.2degrees C and dimercaptosuccinic acid renal scanning and vesicoureteral reflux. Also, there were significant positive correlations between the erythrocyte sedimentation rate, positive urinary nitrite test, hyaline cast, and renal ultrasound and high-grade vesicoureteral reflux.CONCLUSIONS:
This study revealed fever>38.2degrees C and dimercaptosuccinic acid renal scanning as the best predictive markers for vesicoureteral reflux in children with their first febrile urinary tract infection. In addition, erythrocyte sedimentation rate, positive urinary nitrite test, hyaline cast, and renal ultrasound are the best predictive markers for high-grade vesicoureteral reflux.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Urinary Tract Infections
/
Vesico-Ureteral Reflux
/
Blood Sedimentation
/
C-Reactive Protein
/
Biomarkers
/
Cross-Sectional Studies
/
Predictive Value of Tests
/
Sensitivity and Specificity
/
Radiopharmaceuticals
/
Technetium Tc 99m Dimercaptosuccinic Acid
Type of study:
Diagnostic study
/
Observational study
/
Prevalence study
/
Prognostic study
/
Risk factors
Limits:
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
Language:
English
Journal:
Korean Journal of Urology
Year:
2014
Type:
Article
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