Effect of Histological Inflammation on Total and Free Serum Prostate-Specific Antigen Values in Patients Without Clinically Detectable Prostate Cancer
Korean Journal of Urology
;
: 527-532, 2014.
Article
in English
| WPRIM
| ID: wpr-156584
ABSTRACT
PURPOSE:
We are often confronted with patients in the "gray zone" (prostate-specific antigen [PSA]0.010). A correlation existed between inflammation type and fPSA (r=-0.31, p=0.001) and f/tPSA (r=-0.43, p<0.001) in that the fPSA and f/tPSA were lower in the group with more acute inflammation.CONCLUSIONS:
Subclinical inflammation has a significant influence on fPSA in patients with tPSA<10 ng/mL but without PC or clinical prostatitis. Subclinical inflammation is not characterized by elevated tPSA alone but also by a decreased fPSA, a tendency similar to that in PC.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Prostate
/
Prostatic Neoplasms
/
Prostatitis
/
Kallikreins
/
Acute Disease
/
Chronic Disease
/
Prostate-Specific Antigen
/
Diagnosis, Differential
/
Asymptomatic Diseases
/
Biopsy, Large-Core Needle
Type of study:
Diagnostic study
Limits:
Aged
/
Aged80
/
Humans
/
Male
Language:
English
Journal:
Korean Journal of Urology
Year:
2014
Type:
Article
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