Effect of Histological Inflammation on Total and Free Serum Prostate-Specific Antigen Values in Patients Without Clinically Detectable Prostate Cancer
Korean Journal of Urology
; : 527-532, 2014.
Article
in En
| WPRIM
| ID: wpr-156584
Responsible library:
WPRO
ABSTRACT
PURPOSE: We are often confronted with patients in the "gray zone" (prostate-specific antigen [PSA]0.010). A correlation existed between inflammation type and fPSA (r=-0.31, p=0.001) and f/tPSA (r=-0.43, p<0.001) in that the fPSA and f/tPSA were lower in the group with more acute inflammation. CONCLUSIONS: Subclinical inflammation has a significant influence on fPSA in patients with tPSA<10 ng/mL but without PC or clinical prostatitis. Subclinical inflammation is not characterized by elevated tPSA alone but also by a decreased fPSA, a tendency similar to that in PC.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Prostate
/
Prostatic Neoplasms
/
Prostatitis
/
Kallikreins
/
Acute Disease
/
Chronic Disease
/
Prostate-Specific Antigen
/
Diagnosis, Differential
/
Asymptomatic Diseases
/
Biopsy, Large-Core Needle
Type of study:
Diagnostic_studies
Limits:
Aged
/
Aged80
/
Humans
/
Male
Language:
En
Journal:
Korean Journal of Urology
Year:
2014
Type:
Article