99mTc-Tetrofosmin Scintimammography in Suspected Breast Cancer Patients: Comparison with 99mTc-MIBI / 대한핵의학회잡지
Korean Journal of Nuclear Medicine
;
: 119-128, 2000.
Article
in Korean
| WPRIM
| ID: wpr-156780
ABSTRACT
PURPOSE:
The aim of this study was to investigate the diagnostic role of 99mTc-Tetrofosmin in detection of breast cancer and compared with that of 99mTc-MIBI. MATERAL ANDMETHODS:
Forty-eight patients with a clinically palpable mass or abnormal mammographic or ultrasonographic findings had 99mTc-MIBI and 99mTc-Tetrofosmin scintimammographies after intravenous injection of 925 MBq of radiopharmaceuticals. The scintimammographs were correlated with histopathologic findings.RESULTS:
Thirty-three patients were diagnosed with breast cancer and 15 patients with benign breast diseases. The numbers of true positive, true negative, false positive, and false negative cases of 99mTc-MIBI scintimammography were 29, 10, 5, and 4 respectively. The sensitivity, specificity, positive predictive value, and negative predictive value of 99mTc-MIBI scintimammographies were 87.8%, 66.7%, 85.3%, and 71.4% respectively. The numbers of true positive, true negative, false positive, and false negative cases of 99mTc-Tetrofosmin were 31,10, 5, and 2 respectively. The sensitivity, specificity, positive predictive value, negative predictive value of 99mTc-Tetrofosmin were 93.9%, 66.7%, 86.1%, and 73.3% respectively. One patient was false negative in both 99mTc-MIBI and 99mTc-Tetrofosmin scintimammographies and its size was 0.5cm.CONCLUSION:
99mTc-Tetrofosmin and 99mTc-MIBI were non-invasive and useful in detection of breast cancer and 99mTc-Tetrofosmin was comparable to the 99mTc-MIBI in detection of primary breast cancer.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Breast
/
Breast Diseases
/
Breast Neoplasms
/
Sensitivity and Specificity
/
Radiopharmaceuticals
/
Injections, Intravenous
Type of study:
Diagnostic study
/
Prognostic study
Limits:
Humans
Language:
Korean
Journal:
Korean Journal of Nuclear Medicine
Year:
2000
Type:
Article
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