Abnormalties of Ocular Motor Movement in Patients with Parkinson's Disease
Journal of the Korean Neurological Association
;
: 754-760, 1996.
Article
in Korean
| WPRIM
| ID: wpr-157065
ABSTRACT
OBJECTIVE:
We investigated the relationship between the severity of the disease and the abnormality of some ocular movements in parkinson's disease.BACKGROUND:
Disorders of eye movements have been described in diseases of the basal ganglia for over a century and ocular motor deficits of the saccadic and pursuit system have been reported in parkinsonian patients.METHOD:
We studied the electro-oculography of the eye tracking and saccadic movement in 26 patients (11 males, 15 females) with Parkinson's disease. The severity of the disease was divided into two groups by Hoehn & Yahr(H-Y) staging, H-Y stage 1, 2(group A) and H-Y stage 3, 4 (Group B). Some patients antiparkinsonian drugs of L-dopa, dopamine agonist and anticholinergics.RESULT:
The velocity of smooth pursuit and the velocity and latency of saccade were calculated and compared between two groups. Eye tracking test revealed decreased pursuit velocity leading to catch-up saccades, but normal phase relationship between eye and target movement, while saccadic eye movement had increased latency. These results showed more profound severity in more advanced stages of the disease.CONCLUSION:
We suggest that ocular movement be often chosen as a simple but relevant example of general motor function, as well as criteria for staging of Parkinson's disease and basal ganglia play significant role in ocular movement.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Parkinson Disease
/
Pursuit, Smooth
/
Saccades
/
Basal Ganglia
/
Levodopa
/
Dopamine Agonists
/
Cholinergic Antagonists
/
Eye Movements
Limits:
Humans
/
Male
Language:
Korean
Journal:
Journal of the Korean Neurological Association
Year:
1996
Type:
Article
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