Genetic studies of allergic disease and their clinical implications / 대한내과학회지
Korean Journal of Medicine
;
: 416-424, 2009.
Article
in Korean
| WPRIM
| ID: wpr-157165
ABSTRACT
Allergic disease is a complex disorder in which the interaction between environmental and genetic effects may modify both the susceptibility to and severity of the disease. Over the last few years, our understanding of the genetic basis of allergic diseases has improved markedly, which has led to the identification of several chromosome regions and loci showing linkage to allergic disease. As another approach, association studies between candidate gene polymorphisms and allergic diseases have been conducted in many areas and replicated in different ethnic groups. These approaches need to be followed by validation processes to confirm their functional relevance in the pathophysiology of allergic disease. This review updates genetic studies of and recent findings in, allergic disease.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Ethnicity
Type of study:
Prognostic study
Limits:
Humans
Language:
Korean
Journal:
Korean Journal of Medicine
Year:
2009
Type:
Article
Similar
MEDLINE
...
LILACS
LIS