Your browser doesn't support javascript.
loading
A case of hepatoblastoma misdiagnosed as combined hepatocellular carcinoma and cholangiocarcinoma in an adult
Clinical and Molecular Hepatology ; : 300-308, 2015.
Article in English | WPRIM | ID: wpr-157197
ABSTRACT
Hepatoblastoma usually occurs in children under the age of 2 years, with very few cases reported in adults. We experienced a case of adult hepatoblastoma in a 36-year-old female with chronic hepatitis B . She had experienced sudden onset abdominal pain. Her serum alpha-fetoprotein level was markedly elevated, and abdominal CT showed a 9-cm mass with internal hemorrhage in the right hepatic lobe with hemoperitoneum, so an emergency hepatic central bisectionectomy was performed. The initial histologic examination revealed that the mass mimicked combined hepatocellular carcinoma and cholangiocarcinoma with spindle-cell metaplasia of the cholangiocarcinoma element. Follow-up abdominal CT performed 3 months later showed a 5.5-cm metastatic mass in the left subphrenic area. Laparoscopic splenectomy with mass excision was performed, and hepatoblastoma was confirmed histologically. A histologic re-examination of previously obtained surgical specimens also confirmed the presence of hepatoblastoma. Metastatic hepatoblastoma was found at multiple sites of the abdomen during follow-up, and so chemotherapy with cisplatin, 5-fluorouracil (5-FU), and vincristine was applied, followed by carboplatin and doxorubicin . Despite surgery and postoperative chemotherapy, she died 12 months after symptom onset.
Subject(s)

Full text: Available Index: WPRIM (Western Pacific) Main subject: Vincristine / Doxorubicin / Tomography, X-Ray Computed / Cisplatin / Hepatoblastoma / Cholangiocarcinoma / Carcinoma, Hepatocellular / Hepatitis B, Chronic / Diagnostic Errors / Drug Therapy, Combination Type of study: Diagnostic study Limits: Adult / Female / Humans Language: English Journal: Clinical and Molecular Hepatology Year: 2015 Type: Article

Similar

MEDLINE

...
LILACS

LIS

Full text: Available Index: WPRIM (Western Pacific) Main subject: Vincristine / Doxorubicin / Tomography, X-Ray Computed / Cisplatin / Hepatoblastoma / Cholangiocarcinoma / Carcinoma, Hepatocellular / Hepatitis B, Chronic / Diagnostic Errors / Drug Therapy, Combination Type of study: Diagnostic study Limits: Adult / Female / Humans Language: English Journal: Clinical and Molecular Hepatology Year: 2015 Type: Article