Oxaliplatin-induced Pulmonary Fibrosis: Two Case Reports
Journal of the Korean Society of Coloproctology
;
: 266-269, 2011.
Article
in English
| WPRIM
| ID: wpr-157250
ABSTRACT
Oxaliplatin with infusional 5-fluorouracil plus leucovorin (FOLFOX regimen) is the one of the standard chemotherapy regimens for treating a colorectal carcinoma. The most common side effects include neutropenia, diarrhea, vomiting and peripheral neuropathy, and these are moderate and manageable. However, pulmonary toxicity is rarely reported to be associated with the FOLFOX regimen. Moreover, there is no established guideline for the management of this side effect. Here, along with a literature review, we report two cases of rapidly developing pulmonary fibrosis related to the use of the FOLFOX regimen in patients with colorectal carcinomas.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Organoplatinum Compounds
/
Pulmonary Fibrosis
/
Vomiting
/
Colorectal Neoplasms
/
Antineoplastic Combined Chemotherapy Protocols
/
Leucovorin
/
Peripheral Nervous System Diseases
/
Diarrhea
/
Fluorouracil
/
Neutropenia
Limits:
Humans
Language:
English
Journal:
Journal of the Korean Society of Coloproctology
Year:
2011
Type:
Article
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