Rituximab-CHOP Induced Interstitial Pneumonitis in Patients with Disseminated Extranodal Marginal Zone B Cell Lymphoma
Yonsei Medical Journal
;
: 155-158, 2008.
Article
in English
| WPRIM
| ID: wpr-158187
ABSTRACT
A 69-year-old male was diagnosed in February 2004 with stage IV extranodal marginal zone B cell lymphoma involving the mediastinal nodes, lung parenchyma and bone marrow with high LDH. Shortness of breath developed following the 5th course of Rituximab-CHOP chemotherapy (cyclophosphamide, Vincristine, Doxorubicin, Prednisolone). Bronchoscopy guided transbronchial lung biopsy revealed interstitial thickening and type II pneumocyte activation, compatible with interstitial pneumonitis. After treatment with prednisolone a complete resolution of the dyspnea was observed. The patient was well on routine follow-up at the outpatient clinic, with no progression of lymphoma or interstitial pneumonitis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Vincristine
/
Biopsy
/
Prednisone
/
Antineoplastic Combined Chemotherapy Protocols
/
Doxorubicin
/
Tomography, X-Ray Computed
/
Lung Diseases, Interstitial
/
Lymphoma, B-Cell, Marginal Zone
/
Cyclophosphamide
/
Antibodies, Monoclonal
Limits:
Aged
/
Humans
/
Male
Language:
English
Journal:
Yonsei Medical Journal
Year:
2008
Type:
Article
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