Successful desensitization for treatment of an exfoliative dermatitis to allopurinol / 천식및알레르기
Journal of Asthma, Allergy and Clinical Immunology
;
: 980-984, 1999.
Article
in Korean
| WPRIM
| ID: wpr-158712
ABSTRACT
Allopurinol is widely used for chronic tophaceous gout as a uric acid lowering agent. Hypersensitivity to allopurinol occurrs in about 10% of patients, which limits the usage of allopurinol. The successful oral and intravenous desensitization of allopurinol has been reported worldwide since 1976. We recently experienced a 51-year-old male patient with gouty arthritis and hyperuricemia, who had previously experienced skin rash after allopurinol treatment. When allopurinol was retried, erythematous and foliative skin rash developed on entire body. Because allopurinol was essential in controlling hyperuricemia, the oral desensitization of allopurinol was tried. We report successful rapid oral allopurinol desensitization in the patient with chronic tophaceous gout, who exhibited exfoliative dermatitis as allopurinol hypersensitivity.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Uric Acid
/
Arthritis, Gouty
/
Allopurinol
/
Dermatitis, Exfoliative
/
Hyperuricemia
/
Exanthema
/
Gout
/
Hypersensitivity
Limits:
Humans
/
Male
Language:
Korean
Journal:
Journal of Asthma, Allergy and Clinical Immunology
Year:
1999
Type:
Article
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