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A Case of Seizure in Diphenhydramine Overdose
Journal of The Korean Society of Clinical Toxicology ; : 23-25, 2009.
Article in Korean | WPRIM | ID: wpr-159555
ABSTRACT
A 21-year-old woman ingested 1,250 mg of diphenhydramine in a single overdose. Diphenhydramine, a rare ingredient in over-the-counter medication, is used to treat insomnia in Korea. Toxicity is usually limited to anticholinergic symptoms. The standard approach to therapy for the treatment of diphenhydramine overdose is supportive care, including physostigmines and sodium bicarbonates. Here, we review the literature and for the first time report a case of acute diphenhydramine overdosage in Korea, complicated with seizures.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Physostigmine / Seizures / Sodium / Bicarbonates / Diphenhydramine / Sleep Initiation and Maintenance Disorders / Korea Limits: Female / Humans Country/Region as subject: Asia Language: Korean Journal: Journal of The Korean Society of Clinical Toxicology Year: 2009 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Physostigmine / Seizures / Sodium / Bicarbonates / Diphenhydramine / Sleep Initiation and Maintenance Disorders / Korea Limits: Female / Humans Country/Region as subject: Asia Language: Korean Journal: Journal of The Korean Society of Clinical Toxicology Year: 2009 Type: Article