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Risk Factors for Acute Hepatitis A Infection in Korea in 2007 and 2009: A Case-Control Study
Journal of Korean Medical Science ; : 908-914, 2013.
Article in English | WPRIM | ID: wpr-159647
ABSTRACT
This study aimed to identify the risk factors associated with acute hepatitis A virus (HAV) infection in the Korean population. Participants were recruited from five referral hospitals across the country in 2007 and from 11 hospitals in 2009. Patients with positive anti-HAV IgM antibody tests became the case group, while patients treated for non-contagious diseases at the same hospitals were recruited as controls. A total of 222 and 548 case-control pairs were studied in the 2007 and 2009 surveys, respectively. Data from the surveys were analyzed jointly. In a multivariate analysis, sharing the household with HAV-infected family members (OR, 6.32; 95% CI, 1.4-29.6), contact with other HAV-infected individuals (OR, 4.73; 95% CI, 2.4-9.4), overseas travel in 2007 (OR, 19.93; 95% CI, 2.3-174.4), consumption of raw shellfish (OR, 2.51; 95% CI, 1.8-3.5), drinking bottled water (OR, 1.64; 95% CI, 1.3-8.4), and occupation that involve handling food (OR, 3.30; 95% CI, 1.3-8.4) increased the risk of HAV infection. Avoiding contact with HAV-infected individuals and avoiding raw foods eating could help minimize the risk of hepatitis A infection. Immunization must be beneficial to individuals who handle food ingredients occupationally or travel overseas to HAV-endemic areas.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Referral and Consultation / Travel / Immunoglobulin M / Case-Control Studies / Odds Ratio / Acute Disease / Interviews as Topic / Multivariate Analysis / Risk Factors / Vaccination Type of study: Etiology study / Observational study / Prognostic study / Qualitative research / Risk factors Limits: Adolescent / Adult / Child / Child, preschool / Female / Humans / Infant / Male / Infant, Newborn Language: English Journal: Journal of Korean Medical Science Year: 2013 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Referral and Consultation / Travel / Immunoglobulin M / Case-Control Studies / Odds Ratio / Acute Disease / Interviews as Topic / Multivariate Analysis / Risk Factors / Vaccination Type of study: Etiology study / Observational study / Prognostic study / Qualitative research / Risk factors Limits: Adolescent / Adult / Child / Child, preschool / Female / Humans / Infant / Male / Infant, Newborn Language: English Journal: Journal of Korean Medical Science Year: 2013 Type: Article