Bilateral Ovarian Metastases from ALK Rearranged Non-Small Cell Lung Cancer / 결핵및호흡기질환
Tuberculosis and Respiratory Diseases
;
: 258-261, 2014.
Article
in English
| WPRIM
| ID: wpr-159754
ABSTRACT
Anaplastic lymphoma kinase (ALK) rearrangement, is a kind of driver mutation, accounts for 3%-5% of non-small cell lung cancer (NSCLC). NSCLC patients harboring ALK fusion genes have distinct clinical features and good response to ALK inhibitors. Metastasis from lung cancer to the ovary has rarely been known. We report a case of a 54-year-old woman with bilateral ovarian metastases from ALK rearranged NSCLC. She underwent bilateral salpingo-oophorectomy for ovary masses, which were progressed after cytotoxic chemotherapy although primary lung mass was decreased. Histopathological examination of the ovary tumor showed characteristic adenocarcinoma patterns of the lung and ALK rearrangement.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Ovary
/
Phosphotransferases
/
Adenocarcinoma
/
Carcinoma, Non-Small-Cell Lung
/
Drug Therapy
/
Lung
/
Lung Neoplasms
/
Lymphoma
/
Neoplasm Metastasis
Limits:
Female
/
Humans
Language:
English
Journal:
Tuberculosis and Respiratory Diseases
Year:
2014
Type:
Article
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