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A case of ticlopidine induced acute cholestatic hepatitis and pure red cell aplasia / 대한간학회지
The Korean Journal of Hepatology ; : 102-107, 2008.
Article in Korean | WPRIM | ID: wpr-160184
ABSTRACT
Ticlopidine inhibits platelet aggregation and provides beneficial secondary prevention of cerebrovascular and coronary artery disease. Frequently reported adverse effects of ticlopidine include diarrhea, nausea, and rash. However, to our knowledge, there are only a few published reports of the simultaneous occurrence of cholestatic hepatitis and pure red cell aplasia. Here we report a patient with simultaneous severe cholestatic hepatitis and pure red cell aplasia associated with ticlopidine. Although these adverse effects are rare, periodic hematological and liver function tests are recommended after starting ticlopidine.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Ticlopidine / Platelet Aggregation Inhibitors / Cholestasis / Acute Disease / Red-Cell Aplasia, Pure / Chemical and Drug Induced Liver Injury / Liver Function Tests Limits: Female / Humans Language: Korean Journal: The Korean Journal of Hepatology Year: 2008 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Ticlopidine / Platelet Aggregation Inhibitors / Cholestasis / Acute Disease / Red-Cell Aplasia, Pure / Chemical and Drug Induced Liver Injury / Liver Function Tests Limits: Female / Humans Language: Korean Journal: The Korean Journal of Hepatology Year: 2008 Type: Article