Does Low-Dose Heparin Have a Significant Role in Free Flap Surgery?
Archives of Craniofacial Surgery
;
: 162-165, 2017.
Article
in English
| WPRIM
| ID: wpr-160336
ABSTRACT
BACKGROUND:
It is controversial issue that heparin decreases thrombosis for microsurgical anastomosis, and its effective role is under discussion. This study is for proving whether low-dose heparin is preventing thrombosis in free flap reconstruction.METHODS:
Through chart reviews of 134 patients, using low-dose heparin for free tissue transfer from 2011 to 2016, retrospective analysis was performed. 33 patients received low-dose heparin therapy after surgery. And 101 patients received no-heparin therapy. Complications included flap necrosis, hematoma formation, dehiscence and infection.RESULTS:
In no-heparin therapy group, comparing the flap necrosis revealed 16 cases (15.84%). And, flap necrosis was 6 cases (18.18%) in low-dose heparin therapy group. The statistical analysis of flap necrosis rate showed no significant difference (p=0.75). The results showed that there was no significant difference of flap necrosis rate between two groups.CONCLUSION:
In this study, patients in the low-dose heparin group had no significantly lower rates of flap failure compared with no-heparin group. This suggests that low-dose heparin may not prevent thrombosis and subsequent flap failure to a significant extent.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Thrombosis
/
Heparin
/
Retrospective Studies
/
Free Tissue Flaps
/
Hematoma
/
Necrosis
Type of study:
Observational study
Limits:
Humans
Language:
English
Journal:
Archives of Craniofacial Surgery
Year:
2017
Type:
Article
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