Transfusion - Associated Graft - Versus - Host Disease in Patients with Acute Leukemia / 대한피부과학회지
Korean Journal of Dermatology
; : 345-349, 1996.
Article
in Ko
| WPRIM
| ID: wpr-161063
Responsible library:
WPRO
ABSTRACT
Graft-versus-host disease can develop in immunosuppressed individuals who receive blood product transfusions that contain imrnunocompetent lymphocytes. We report a case of transfusion-associated graft-versus-host disease(TA-GVHD) that developed in a patient with acute lymphocytic leukemia who were undergoing therapy. The groups at risk for development of TA-GVHD, the clinical presentation and course, and methods of diagnosis are summarized. Prevention of TA-CVHD is possible by irradiation of blood products given to patients at risk, but problems remain in determining the groups that warrant such measures. We should be aware of the risk of developing TA-GVHD after routine blood transfusion, especially in areas where the population's HLA types are rather homogeneous.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Blood Transfusion
/
Lymphocytes
/
Leukemia
/
Transplants
/
Diagnosis
/
Precursor Cell Lymphoblastic Leukemia-Lymphoma
/
Graft vs Host Disease
Type of study:
Diagnostic_studies
Limits:
Humans
Language:
Ko
Journal:
Korean Journal of Dermatology
Year:
1996
Type:
Article