A Case of Primary Cutaneous CD30 Positive Large Cell Lymphoma / 대한피부과학회지

ABSTRACT

Primary cutaneous CD30(Ki- 1) positive large cell lymphoma occurs generally in adults and in contrast to primary noncutaneous CD30 positive large cell lymphoma, rarely in children and adolescences. Generally it does not express epithelial membrane antigen(EMA). Recently we experienced a sixteen-year old boy who developed CD30 positive large cell lymphoma. He presented with single ulcerative nodule on his right upper vermilion border and there was no evidence of lymph nodal or other visceral involvement. In paraffin section, stainings for CD30, CD45RO, CD45 and EMA were positive but staining for CD20 was negative. His young age of onset and positive immunoreactivity to EMA of tumor cells in this case are unusual features for primary cutaneous CD30 positive large cell lymphoma.