Diagnosis of Chlamydia trachomatis Infection from Transcervical Cells of Pregnant Women by PCR Assay / 대한주산의학회잡지
Korean Journal of Perinatology
;
: 152-158, 1998.
Article
in Korean
| WPRIM
| ID: wpr-161699
ABSTRACT
BACKGROUND:
Chlamydia trachomatis is most common sexually transmitted pathogen in the world, and a common cause of urethritis and cervicitis. Also it is common cause of preterm premature rupture of membranes and premature labor in pregnant women, and pneumonitis and conjunctivitis in neonate. A rapid and sensitive polymerase chain reaction(PCR)-based assay for detection of C. trachomatis is recently introduced.OBJECTIVES:
We studied to determine whether a PCR assay is useful to detect Chlamydial infection in pregnant women. We also studied to compare its prevalence rate according to maternal age, trimester and parity, respectively. StudyDesign:
Specimens were collected from 149 pregnant women by transcervical swab or endocervical lavage. If a specific band was detected in PCR assay, we considered as Chlamydial infection.RESULTS:
In general, the positive bands were detected in the 45 of 149 pregnant women(30.2%). The positive bands were detected the 6 of 55(10.9%), 16 of 49(32.7%), and 23 of 45(51.1%) pregnant women in each trimester, respectively. Therefore, there was significantly increased according to the gestational age(p 0.05).CONCLUSION:
We concluded that the PCR assay is a fast and useful test for the detection of C. trachomatis in transcevical cells from the pregnant women. This study suggested that Chlamydial infection seems to be increased according to the gestational age.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Parity
/
Pneumonia
/
Rupture
/
Urethritis
/
Uterine Cervicitis
/
Chlamydia
/
Chlamydia trachomatis
/
Polymerase Chain Reaction
/
Prevalence
/
Gestational Age
Type of study:
Diagnostic study
/
Prevalence study
Limits:
Female
/
Humans
/
Infant, Newborn
/
Pregnancy
Language:
Korean
Journal:
Korean Journal of Perinatology
Year:
1998
Type:
Article
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